Kind of hard to give hints for that without just flat out spoiling it.

Spoiler: Hint / Answer to the blinking E yes

You will need to figure out why the numbers are on the walls next to the decals, and then with the answer to that, apply that to all of the other decals throughout the room. After that, the blinking E yes may blink a certain amount of times each, add them together. Sorry if this is too much or not enough.

 

Spoiler: Hint

When you get teleported into the room, that starting 4 directions is kind of a tutorial area for the room. If you can figure out why the 3 different paths kill you and why the 1 doesn't kill you, you can apply that for the longer, more complex area to get to the end.

Spoiler: The actual answer to it

If you step onto a color tile to start it, you cannot step onto the same color tile for the next one. Once you step onto the next different color tile, you cannot step onto the previous tile color, and the current tile color you are on. Once you step onto the 3rd tile color, you can once again step onto that first tile color you went on. You apply this to find a path to the end.

Other notes for this part:
-You cannot go diagonal (however you sometimes can get lucky and if you get into an area where no tiles are safe, I would recommend trying to get lucky doing it)
-The white tiles (starting teleporter tile, and the long one at the start of the big floor of color tiles) resets the tiles you were just on (can walk on any color again)

And I got a few messages asking about once you reach the end of the color tile path.

Spoiler: Hint

The object at the end of the path with the red thing on it, can be found in another area. The red thing represents an interact on said object. You do however, have to walk the color tile path to unlock the interact on said object.